Leucine

Amino acid that helps muscle health, regulates blood sugar

  • Essential amino acid; found in protein foods
  • Can get enough from well balanced diet that includes proteins
  • If meatless diet, eat a variety of plant based proteins to get all 9 amino acids

Health Benefits:

  • growth and repair of muscle, skin, bone
  • prevents muscle deterioration with age
  • may increase production of human growth hormone
  • may help control blood sugar

Low intake of Leucine

Symptoms of low Leucine intake

  • Fatigue
  • Gastrointestinal problems
  • Hair loss
  • Low blood sugar
  • Skin rashes
  • Weight loss, Decreased appetite

Causes of low Leucine intake

  • Common in older people
  • Leads to muscle weakening, tremors

Excess intake of Leucine

Symptoms of excess intake of Leucine

  • Bloating
  • Fatigue
  • Gastrointestinal problems
  • Headache, High BP
  • Insulin resistance
  • Loss of coordination

At risk for excess Leucine

  • Can't overdose from food
  • Caution supplements: if taken for > 6 months can cause side effects

Leucine Content in Foods

Foods High in Leucine

FoodServing SizeLeucine
Ribeye steak, grilled6 oz4.8 g
Chicken breast, lean6 oz4.5 g
Pork chop, lean6 oz4.3 g
Tofu, firm1 cup3.5 g
Tilapia, cooked6 oz3.5 g
Beef chuck pot roast3 oz2.3 g
Soybeans (edamame), boiled1 cup2.3 g
Oats, uncooked1 cup2 g
White tuna, canned, oil packed3 oz1.83 g
Navy beans, canned1 cup1.67 g

Foods Low in Leucine

FoodServing SizeLeucine
Celery stalk1 large0.02 g
Greens, lettuce1 cup0.02 g
Dates3 dates0.02 g
Apples, chopped1 cup0.02 g
Orange juice1 cup0.03 g
Grape juice1 cup0.03 g
Cucumber, lettuce, kale1 cup0.03 g
Green, red grapes1 cup0.03 g
Orange sections, Pineapple chunks, Peaches1 cup0.04 g
Cherries, sweet1 cup0.05 g

References

Leucine Purported Benefits, Side Effects & More. (2022). Memorial Sloan Kettering Cancer Center. https://www.mskcc.org/cancer-care/integrative-medicine/herbs/leucine
Leucine (g). (n.d.). U.S. DEPARTMENT OF AGRICULTURE, FoodData Central. https://fdc.nal.usda.gov/fdc-app.html#/?component=1213
Nutrients: Leucine (g). (n.d.). USDA National Nutrient Database for Standard Reference. Retrieved November 6, 2023, from https://www.nal.usda.gov/sites/default/files/page-files/leucine.pdf
Wappner, R., & Gibson, K. (2003). Disorders of Leucine Metabolism. Physician’s Guide to the Laboratory Diagnosis of Metabolic Diseases 2nd ed. http://eknygos.lsmuni.lt/springer/365/59-79.pdf

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